This includes the autosomal recessive conditions NBS, ATLD, and NBS-like disorder (NBSLD), where the NBS1, MRE11, and RAD50 genes, respectively, contain loss-of-function mutations (Ciccia and Elledge, 2010, Jackson and Bartek, 2009, O’Driscoll and Jeggo, 2006, Waltes et al., 2009). This evidence concerns the gene RAD50 and Nijmegen breakage syndrome-like disorder.