Conversely, with respect to subjects with T2D at baseline, PON1 and Cp activity were correlated with HDL-cholesterol (r = 0.78, p = 0.003, CI 0.35–1.00) and CRP (r = 0.66, p = 0.019, CI 0.13–1.00), respectively; further, pHDL was significantly associated with LDL-cholesterol (r = 0.59, p = 0.042, CI 0.03–1.00). This evidence concerns the gene PON1 and type 2 diabetes mellitus.