There were no mitotic marker phospho-histone H3 (PH3)-positive signals in NSCs overexpressing miR-17-92 cluster (miR-17-92-NSC) as well as control cells (CON-NSC) 1 day (Fig. 5c) and 7 days (data not shown) after transplantation, excluding the possibility of tumor formation which also indicates that miR-17-92 cluster has little effect on NSC proliferation in the lesioned brain. The gene discussed is PHC3; the disease is neoplasm.