Plasma adiponectin concentration was significantly associated with MetS (OR, 95 % CI: 0.829, 0.762- 0.902 for MetS-IDF, and 0.840, 0.772- 0.914 for MetS-AHA/NHLBI) (Table 4), whereas plasma IL-6 concentration was not significantly associated with MetS (Table 5). The gene discussed is ADIPOQ; the disease is autoimmune hemolytic anemia.