We found that stage (P = 0.050), tumour status (P = 0.001), DNASE1L3 expression (P = 0.042), and INTS8 expression (P = 0.023) were independent risk prognostic factors for OS in HCC patients, although no gene was found to be an independent prognostic factor for DFS (data not shown). Here, DNASE1L3 is linked to neoplasm.