CDH1 and adenoma: Co-infection of ApcΔ/ΔCdh1fl/flLgr5CreERT2 adenoma cells with a CMV promoter driven adenovirus expressing either murine wild-type or an EC1 domain mutated Cdh1 cDNA, were combined in vectors with an IRES for the fluorescent reporter RFP (Ad-Cdh1-WT-RFP or Ad-Cdh1-Mut-RFP).