GPT and viral encephalitis: In the 26 patients with organ failure, respiratory distress (11 patients [42.3%]), AST levels >1000 IU/L and/or ALT >1000 IU/L (9 patients [34.6%]), serum creatinine concentration ≥3-fold greater than baseline (6 patients [23.1%]), spontaneous gastrointestinal bleeding requiring blood transfusion (6 patients [23.1%]), myocarditis (4 patients [15.4%]), and encephalitis (3 patients [11.5%]) were observed.