Ohori et al. [1] from the USA and Steuber et al. [3] from Europe generated the famous MSKCC nomograms based on cStage, PSA, Gleason sum, percentage of positive cores, and percentage of cancer, thus providing predictive accuracies for SS-ECE of 0.806 and 0.840, respectively. The gene discussed is KLK3; the disease is cancer.