AβO-injected rats demonstrated significantly less ambulatory travel distance compared to controls (Figure 1D, control—2245.53 ± 230.49 cm, AβO—1649.44 ± 172.99 cm) and specifically, significantly less ambulatory distance traveled in the central zone compared to controls (Figure 1E, control—26.06% ± 4.32%, AβO—14.73% ± 2.37%), indicating an anxiety-like thigmotactic behaviour. Here, ABO is linked to Anxiety.