Wynter et al. analyzed eight methylation markers (MINT1, MINT2, MINT12, and MINT31 markers, and promoter regions of HPP1, MGMT, p14, and p16) in sporadic and FAP adenoma samples and suggested that FAP adenoma might develop through non-CIMP pathway [24]. The gene discussed is MGMT; the disease is Familial adenomatous polyposis.