NFKB1 and Hodgkins lymphoma: Two key EBV genes involved in the etiology of HL are: latent membrane protein (LMP) 1 (lmp1), which induces constitutive nuclear factor-kappaB (NF-κB) activation by mimicking CD40 receptor [18], and lmp2A, which can take over the function of the B-cell receptor (BCR) [19].