MAGEB2 gene, expressed both by C57BL/6 mice [16] and B16F10 melanoma cells (our observation), was selected as a reference antigen for measuring MA-specific T cell response because MAGE antigens are AIRE-dependent antigens expressed by mTECs [17–21] and have been suggested to be tumor rejection antigens [22, 23]. Here, MAGEB2 is linked to neoplasm.