CRP and chronic obstructive pulmonary disease: A similar variable period was also observed in a sequential COPD-AE-RW rat model, where the levels of inflammatory indicators, such as the number of WBCs and neutrophils and serum amyloid A (SAA) and CRP levels, varied rapidly for 5 days in the AE phase, but the changes were mild in the subsequent 10 days of the RW phase [14, 15].