Lysozyme gene expression was investigated using a database of a genome‐wide gene expression study of wild‐type (WT) and five mouse models of AD (mutant human AβPP, mutant human PSEN1, homozygous and heterozygous expressed AβPP–PSEN1 and mutant human TAU) 15, and a database of AD patient brain tissue 16. Here, PSEN1 is linked to Alzheimer disease.