TCGA-A tumours showed higher expression of most group I/FTEC epithelial proteins such as KRT7, MSLN, CDH6, ASS1 and EPCAM, while TCGA-B tumours had higher expression of the group III/IOSE mesenchymal proteins ITGA5, HMOX1, SMTN and GJA1 (refs 7, 34; Fig. 5b). This evidence concerns the gene ITGA5 and neoplasm.