The predictive validity of type 1 diabetes diagnoses based on discharge codes from the National Patient Registry or on redeemed insulin prescriptions was in 1996 estimated to be 96% in the general population and in 2007 to be 94% to 97% in children.[32;33] There are several potential pathogenic explanations to the findings of an association between redemption of broad-spectrum antibiotics within the first two years of life and increased risk of childhood type 1 diabetes only in children delivered by cesarean section. This evidence concerns the gene INS and type 1 diabetes mellitus.