Notably, the relative amounts of sphingomyelin (SM), phosphatidylcholine (PtdCho), ethanolamine plasmalogen (PtdEtn_pl) and an unidentified PL ("b") were significantly lower in ABCB5-WT vs. ABCB5-KD melanoma cells, whereas the relative amounts of alkyl-acyl PtdCho (AAPtdCho) and another PL subgroup (PtdCho_utot = sum of PtdCho derivatives PtdCho_u1 to PtdCho_u4) were significantly higher. The gene discussed is ABCB5; the disease is melanoma.