PROM1 and central nervous system cancer: Increased glycolysis has also been observed for breast cancer stem cells obtained from patients [9], for the CD133-positive colon carcinoma cell line Colo205 [10], for a murine model of LDH (lactate dehydrogenase)-A-expressing NSCLC [11], and for glioma stem-like cells [12], although there is a report of glioma stem cells with reduced glycolysis and increased oxidative phosphorylation [13].