CD40LG and dengue disease: The frequency of total IgM ASC/106 PBMCs in the infants with dengue compared with severe form of dengue was 1,800 (370–12,000) and 5,200 (1,100–30,000), respectively (P = 0.06, Mann-Whitney test) (Fig 6A); the frequency of E protein-specific IgM ASC/106 PBMCs was 240 (5–4,000) and 1,271 (120–7,680), respectively (P = 0.07, Mann-Whitney test) (Fig 6A), showing a tendency for higher elevation of total and specific IgM ASC in children with SD.