In addition, no significant differences were detected in levels of high-density lipoprotein (HDL) (MD = -0.03, 95% CI: -0.16, 0.11, P = 0.72), glucose (MD = 0.07, 95% CI: -0.51, 0.65, P = 0.81), insulin (MD = 3.26, 95% CI: -2.99, 9.52, P = 0.31), and homeostatic model assessment of insulin resistance (HOMA-IR) (MD = 0.39, 95% CI: -0.33, 1.11, P = 0.29) (Fig 4). Here, INS is linked to Insulin resistance.