The transplanted tumours had either no change in these three genes (infected with lentiviruses carrying an empty vector) or RNF20 knockdown (infected with lentiviruses carrying RNF20 short hairpin RNAs (shRNAs)), RNF40 knockdown (infected with lentiviruses carrying RNF40 shRNAs), or Eg5 knockdown (infected with lentiviruses carrying Eg5 shRNAs). This evidence concerns the gene RNF20 and neoplasm.