Interestingly, it has been shown that Bcr-Abl/Stat5 inhibition induces apoptosis in CML cells by supressing Stat5-dependent transcriptional regulation of Bcl-2 family members such as Mcl-1 [22] and Bcl-xL [43]. Here, BCL2L1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.