Although the aberrant expression of SEPT2 and SEPT7 had been found to associate with various human cancer types including glioma, hepatoma, renal cell carcinoma, leukemia, and lymphoma [2, 10, 15, 30], there are only limited studies systematically evaluating their functional roles in tumoigenesis. This evidence concerns the gene SEPTIN6 and hereditary clear cell renal cell carcinoma.