Although SEPT6 is definitely crucial for Septin organization, its currently biological functions are far less clear and mainly associated with neuron development [24, 25], the other two core members would be more representative to be focused to explore the role of septin proteins in breast cancer biology as plenty of investigation discovered the importance of SEPT2 and SEPT7 within human cancer development [15, 26–30]. Here, SEPTIN7 is linked to breast cancer.