More consistently, SEPT2 and SEPT7 silenced cells performed less invasive abilities into collagen matrix (Figure 4D and 4E); we further confirmed the results by a competitive invasion assay via mixing equal amount of SEPT2 or SEPT7 silenced cell (Green or Red) with control siRNA treated cells (Red or Green), showing reduction in either SEPT2 or SEPT7 protein would induce remarkable suppression on BC cell invasive potentials(Figure 4F). Here, SEPTIN7 is linked to breast cancer.