LCK and systemic lupus erythematosus: Although the SLE patients with greatly decreased JKAP levels in T cells (< 0.2 fold) all exhibited the increased percentages of phospho-Lck-positive T cells (> 4.34%) compared to healthy controls, other SLE patients with normal JKAP levels in T cells also had increased population of phospho-Lck-positive T cells (Supplementary Figure S3).