Thus, in view of studies reporting TF expression by endothelial cells to enhance angiogenesis [5] and TF to be expressed on endothelial cells within the tumor vasculature [4–9], it is tempting to speculate that inhibition of endothelial TF expression by WIN 55,212-2 along with a moderate cytotoxic action may contribute to the anti-angiogenic properties reported for this cannabinoid [75, 76]. The gene discussed is TF; the disease is neoplasm.