Additionally investigations into regulation of activation of APC (i.e., MHC-II) by miR-155 via pathways involving molecules such as c-Fos, SHIP1, SOCS-1 and cytokines, IL-12 and IL-6, are warranted for a better understanding of Ag-specific IFN-γ production in Ct infections [32, 47, 48]. This evidence concerns the gene FOS and infection.