CHKA and colorectal carcinoma: The qPCR results showed that the relative expression of CHKA mRNA was significantly higher in the cancerous tissues than adjacent non-cancerous tissues (Figure 1D, p < 0.01), with 87.3% (55/63) of the CRC tissue specimens tested showed a higher expression level of CHKA mRNA when compared to matched non-cancerous counterparts (Figure 1E).