TP53 and neoplasm: When correlating p53 status with subgroup information, which was available for 102 samples (ST-EPN-RELA (n = 38), PF-EPN-A (n = 60) and PF-EPN-B (n = 17)), it was striking that 89% (n = 34/38) of the supratentorial RELA-positive tumours exhibited p53 accumulation (Figure 1C).