The enhancing effect of NEAT1 on BCSCs is not restricted to MCF10DCIS cells as NEAT1 is also crucial for maintaining self-renewal of BCSCs in basal and luminal breast cancer cell lines HCC1937 and MCF7, evidenced by the inhibitory effect of NEAT1 knockdown on the BCSC sphere formation of HCC1937 and MCF7 cells (Supplementary Figures S3 and S4). The gene discussed is NEAT1; the disease is breast cancer.