ETS2 and esophageal squamous cell carcinoma: Firstly, we confirmed whether Ets2 expression level was elevated in ESCC cells by Western blotting and the results demonstrated that the Ets2 expression was increased by 3.2-fold in EC9706 cells (P < 0.01), 2.2-fold in Eca109 cells (P < 0.05), and 1.93-fold in EC1 cells (P < 0.05) respectively compared with that in Het-1A cells (Figure 1A and 1B).