RPS6KB1 and esophageal squamous cell carcinoma: Our previous study found that the mTOR/p70S6K signaling pathway was aberrantly activated in ESCC cells [24] and that the activity of mTOR/p70S6K signaling pathway was decreased when Prdx1, a tumor-associated antigen in ESCC [25], was reduced in EC9706 cells [26].