N-f-5HT attenuated the upregulation of mRNA and proteins of ROS-dependent adhesion (vascular cell adhesion protein-1 (VCAM-1)) and migration factors (monocyte chemoattractant protein-1 (MCP-1)), crucial in early atherosclerosis lesions in human aortic endothelial cells, and inhibited the activation of transcription factor NF-κB [21]. The gene discussed is VCAM1; the disease is atherosclerosis.