Activation of PPARγ can decrease endotoxemic-induced [32], lipopolysaccharide-induced [9], and hemorrhage-induced [31] acute pulmonary inflammation and injury through inhibition of neutrophil accumulation, ICAM-1 expression, and proinflammatory cytokine (IL-6, IL-1β) production [33]. The gene discussed is PPARG; the disease is inflammatory response.