TYRO3 and Zika virus infectious disease: This broad tissue tropism is likely related to the wide distribution of the candidate receptors of ZIKV, including AXL, TYRO3 and DC-SIGN, in different organs.23 The placental (JEG-3) and neuronal (SF268) cell line tropism corroborated with the congenital and neurological manifestations of ZIKV infection.