Moreover, large, long-term clinical studies of GH therapy have demonstrated no increased risk of neoplasms or recurrent tumors in pediatric patients (Allen et al. 1997, Sävendahl et al. 2012, Patterson et al. 2014, Raman et al. 2015) or in adults (Olsson et al. 2012, Hartman et al. 2013, Brignardello et al. 2015, Child et al. 2015, Stochholm & Johannsson 2015). The gene discussed is GH1; the disease is neoplasm.