Several studies in this analysis reported inverse associations of ghrelin to tumor progression, suggesting a protective effect (D’Onghia et al. 2007, Lin & Yin 2007, Moschovi et al. 2008, Trivin et al. 2009, Holmer et al. 2010), which could involve anti-inflammatory actions (Bataar et al. 2011, Kawaguchi et al. 2015). This evidence concerns the gene GHRL and neoplasm.