GHRL and colorectal cancer: Several studies in gastric, gastroesophageal, and colorectal cancers found either no difference in serum ghrelin levels in cancer patients vs controls (Isomoto et al. 2005, Huang et al. 2007, Tsolakis et al. 2008, Benedix et al. 2011, Zub-Pokrowiecka et al. 2011), or lower ghrelin levels in cancer patients (Kemik et al. 2012, Sadjadi et al. 2013) (Table 1).