BDNF and post-traumatic stress disorder: Coherent oscillatory activity is required for sensory perception, sleep and fear regulation,2 behaviors that are impaired in PTSD,2, 34, 35, 36 and linked to BDNF signaling.8, 9 Because BDNF signaling has a critical role in synaptic plasticity and regulation of excitatory/inhibitory balance, it is a likely candidate for regulating brain oscillatory activity.