The role of CRP in CD has been largely investigated: to detect and differentiate IBD from irritable bowel syndrome,41 to monitor disease activity, to evaluate treatment response42,43 and to predict disease course.17,37 There is clear correlation between CD and increased CRP serum concentration and although its use in predicting clinical relapse and postoperative recurrence has been suggested,44 the value of CRP levels after surgery as a prognostic factor has not been investigated as yet. Here, CRP is linked to irritable bowel syndrome.