OR2AT4 and acute myeloid leukemia: A previous study characterized OR2AT4 in transfected HEK293 cells, the HaCaT cutaneous cell line and primary keratinocytes determining the specific agonists Sandalore, Javanol and Brahmanol and the antagonists Phenirat and Oxyphenilon.14 Our experiments showed that, in both K562 and AML cells, Sandalore activated the OR2AT4 by a cAMP-mediated pathway, via L-type calcium channels, which contribute to the influx of extracellular Ca2+ downsteam.