PGK1 and cancer: A series of enzymes involved in glucose metabolism are responsible for the metabolic alterations during tumorigenesis, for example, glucose transporter 1 (GLUT1),5 phosphofructokinase (PFK),6 phosphoglycerate kinase 1 (PGK1),7 pyruvate kinase, muscle (PKM),8 lactate dehydrogenase A (LDHA).9 These genes are deregulated in most cancer cells.