In its naive form, citrus pectin (CP) has a limited solubility in water and is unable to interact with Gal-3, but its modified form (MCP) acts as ligand for Gal-3.24 MCP induces apoptosis in multiple myeloma cells resistant to conventional therapies.25 It also inhibits tumor growth, angiogenesis and spontaneous metastasis of breast and colon carcinoma cells in nude mice.26 The gene discussed is LGALS3; the disease is plasma cell myeloma.