These findings are supported by Staedler et al. 9 who showed that doxorubicin when combined with quercetin in human breast cancer cell lines (MCF-7, MDA-MB-231 and MCF-10A) synergistically inhibited cell proliferation and induced apoptosis through the reduction of glutathione and glutathione S-transferase.11 Here, HPGDS is linked to breast carcinoma.