CIDEA and neoplasm: Among the three members of cell death-inducing DFFA-like effector (CIDE) protein family, the role of CIDEA in lipid metabolism is documented.1 CIDEA is also known to induce apoptosis.2 Though a low expression level of CIDEA in different malignancies including glioblastoma multiforme (GBM) is documented,3 the mechanisms of its regulation and role in tumor progression remain unexplored.