TNF and glioblastoma: 18 Several cell-based studies employed CMPD1 as a MK2 inhibitor at various concentrations (0.3–50 μM30–34); but only one study demonstrated that CMPD1 at 10 μM inhibited TNF-α induced activation of the MK2 pathway.35 We present here that in U87 glioblastoma cells, CMPD1 at concentrations up to 10 μM did not inhibit the activation of MK2 and Hsp27.