SUV39H1 and rhabdomyosarcoma: Given that higher levels of KMT1A contribute to impaired myogenic differentiation in alveolar subtype of rhabdomyosarcoma [38], and that p38 activity is deficient in a majority of rhabdomyosarcoma tumors regardless their subtype [39], it remains to be determined whether and to what extent dysregulated p38γ/α-KMT1A signaling axis contributes to restraining rhabdomyosarcoma differentiation, a question of therapeutic significance.