BMI1 and breast carcinoma: 2013). This study demonstrates that CUR reduces BMI1 expression in breast cancer cells by upregulating miR‐34a (Guo et al. 2013). However, to the best of our knowledge, our study is the first to show that CUR reduces BMI1 expression in colorectal cancer cells. Therefore, our future studies will focus on understanding if CUR reduces BMI1 levels by upregulating one or more of the miRNAs shown to downregulate BMI1 expression (Bhattacharya et al. 2009; Saini et al. 2011; He et al. 2012; Liu et al. 2012; Sun et al. 2012; Guo et al. 2014; Jin et al. 2014; Yu et al. 2014; Jones et al. 2015).