RGS2 and polyostotic fibrous dysplasia: In addition, RGS2+/+ mice treated with PFD exhibited significantly higher lung compliance than mice treated with vehicle (0.023 ± 0.001 vs. 0.014 ± 0.001, p < 0.01) (Fig. 6c), indicating that the bleomycin-induced loss of lung compliance was attenuated by PFD treatment.