The proportion of subjects in the comparison group who used insulins and insulin analogs without concomitant treatment with T2DM medication, i.e. primarily individuals with T1DM, was 0.67%, a similar proportion to that seen in the population in general in Sweden.28 The proportion of individuals with T1DM treatment in the obese cohort was much lower. This evidence concerns the gene INS and type 1 diabetes mellitus.