This interaction of tumor treatment by time was statistically significant for Tnfα (F1,36 = 6.2, p<0.05), Cxcl2 (F1,36 = 5.7, p <0.05), Cxcl10 (F1,36 = 8.5, p<0.01), Tgf-β (F1,33 = 6.8, p<0.01), and Igf-1 (F1,36 = 8.4, p<0.01). This evidence concerns the gene IGF1 and neoplasm.