MMP9 and non-alcoholic fatty liver: In this report, we observed that KMUP-1 affected high-fat diet (HFD)-induced hyperadiposity in livers through matrix metallopeptidase 9 (MMP-9) and reactive oxygen species (ROS) inhibition, and HSL/p-HSL and IL-10 stimulation, suggesting that it might be a potential candidate for strengthening the therapy of nonalcoholic fatty livers.