NOS3 and pulmonary arterial hypertension: For example, Pan et al.8 reported that electroacupuncture (EA) at feishu (BL13) and xinshu (BL15) acupoints protected against pulmonary hypertension by regulating the activity of endothelium-derived endothelin 1 (ET-1) and endothelial nitric oxide synthase (eNOS).