Luminex data on aqueous humor cytokine profiles from HIV patients with CMV retinitis revealed 9 cytokines G-CSF, IL-8, IFN-g, IP-10, fractalkine, IL-12p70, MCP-1, IL-10 and IL-6 showed a statistically significant negative correlation for samples analyzed longitudinally over the 4 times points (Table 1) and 9 cytokines MCP-1, IFN-g, IP-10, IL-8, fractalkine, RANTES, PDGF-AA, FLT-3L and G-CSF showed statistically significant positive correlation with CMV DNA viral load through course of treatment (Table 2). Here, CX3CL1 is linked to cytomegalovirus retinitis.