At postmortem the brain of AD patients presents with neurodegeneration mostly affecting the medial temporal lobe and neocortical structures.3 AD is characterized pathologically by accumulation of amyloid beta (Aβ) peptides, seen as senile plaques, and hyper‐phosphorylated Tau protein apparent as neurofibrillary tangles. The gene discussed is MAPT; the disease is Alzheimer disease.